TOP PKRRATING SECRETS

3B). R526 from your loop concerning αJ and αI anchors the C-terminal part of the activation loop by forming a salt bridge with E458 at The bottom of αEF. Q459 stabilizes the HRD motif by a hydrogen bond to the main chain carbonyl of R413. The tip of the activation segment is stabilized by a hydrogen bond between Y454 and E480 from αF. In the FT

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